The researchers have identified new cases of colorectal cancer in this way as they analysed 443 colon cancer patients followed over more than five years: :::[SMH]
This is not the first time a link between reduced cancer risk and exercise has been found:
Among subjects who were physically active, an increase in
IGFBP-3 was associated with a 48 per cent reduction in colon
cancer-specific deaths. No association was apparent for IGF-1.
For the physically inactive, there was no association between
IGF-1 or IGFBP-3 and colon cancer survival.
Haydon said that "physical activity can increase IGFBP-3 levels,
which, in turn, reduces the amount of free IGF-1". IGF-1 has been
shown to stimulate cell growth, inhibit cell death, and promote
angiogenesis - the formation of new blood vessels, which tumours
need to grow.
"Other studies that have looked at this have shown aOther blogs on: health, exercise, healthy living, cancer
dose-effect, meaning the more exercise the lower the risk, however
our study did not try to address this issue. We were examining the
effect of physical activity on one's prognosis following a
diagnosis of bowel cancer and the possible mechanisms behind this